NDUFA1 -> Complex_1_complex
NDUFB9 -> Complex_1_complex
csa98_mtDNA_encoded_OXPHOS_units_complex_mitochondrial_matrix -> Complex_1_complex
OXPHOS_factors_complex -> Complex_1_complex
NADH_simple_molecule -> Complex_1_complex
Complex_1_complex -> Complex_1_complex
mt_mRNA_rna -> csa60_mtDNA_encoded_OXPHOS_units_complex_mitochondrial_matrix
Mt_translation_complex -> csa60_mtDNA_encoded_OXPHOS_units_complex_mitochondrial_matrix
Mt_ribosomal_proteins_complex -> csa60_mtDNA_encoded_OXPHOS_units_complex_mitochondrial_matrix
Nsp8_affected_Mt_ribosomal_proteins_complex -> csa60_mtDNA_encoded_OXPHOS_units_complex_mitochondrial_matrix
ACAD9 -> OXPHOS_factors_complex
ECSIT -> OXPHOS_factors_complex
NDUFAF7 -> OXPHOS_factors_complex
sa205_SIRT3_mitochondrial_matrix -> csa24_complex_2_complex_mitochondrial_matrix
OXPHOS_factors_complex -> csa24_complex_2_complex_mitochondrial_matrix
csa84_complex_2_complex_mitochondrial_matrix -> csa24_complex_2_complex_mitochondrial_matrix
sa219_Q_simple_molecule_mitochondrial_matrix -> csa24_complex_2_complex_mitochondrial_matrix
Complex_1_complex -> csa24_complex_2_complex_mitochondrial_matrix
csa103_mtDNA_encoded_OXPHOS_units_complex_mitochondrial_matrix -> complex_3_complex
OXPHOS_factors_complex -> complex_3_complex
Complex_1_complex -> complex_3_complex
sa219_Q_simple_molecule_mitochondrial_matrix -> complex_3_complex
csa24_complex_2_complex_mitochondrial_matrix -> csa84_complex_2_complex_mitochondrial_matrix
TCA_phenotype -> csa84_complex_2_complex_mitochondrial_matrix
sa20_H__ion_Intermembrane_space -> ATP_Synthase_complex
sa644_H__ion_Intermembrane_space -> ATP_Synthase_complex
sa18_H__ion_Intermembrane_space -> ATP_Synthase_complex
ATP5MG -> ATP_Synthase_complex
Nsp6 -| ATP_Synthase_complex
csa103_mtDNA_encoded_OXPHOS_units_complex_mitochondrial_matrix -> complex_4_complex
OXPHOS_factors_complex -> complex_4_complex
complex_3_complex -> complex_4_complex
sa253_Cyt_C_mitochondrial_matrix -> complex_4_complex
paraquat_simple_molecule -> paraquat_dication_complex
sa361_O_2__simple_molecule_mitochondrial_matrix -> paraquat_dication_complex
mt_DNA_gene -> MT_tRNAs_complex
Mt_tRNA_synthetase_complex -> MT_tRNAs_complex
TRMT1 -> MT_tRNAs_complex
Nsp8 -| Nsp8_affected_Mt_ribosomal_proteins_complex
TIMM29 -> TIM22_complex_complex
NSP4 -| TIM22_complex_complex
NSP4 -| TIM9_TIM10_complex_complex
NADH_simple_molecule -> NAD__simple_molecule
Complex_1_complex -> NAD__simple_molecule
sa24_O_2__simple_molecule_mitochondrial_matrix -> sa6_Q_simple_molecule_mitochondrial_matrix
sa13_Cyt_C_mitochondrial_matrix -> sa6_Q_simple_molecule_mitochondrial_matrix
sa19_H__ion_mitochondrial_matrix -> sa6_Q_simple_molecule_mitochondrial_matrix
sa255_QH_2__simple_molecule_mitochondrial_matrix -> sa6_Q_simple_molecule_mitochondrial_matrix
complex_3_complex -> sa6_Q_simple_molecule_mitochondrial_matrix
Complex_1_complex -> sa18_H__ion_Intermembrane_space
sa24_O_2__simple_molecule_mitochondrial_matrix -> sa20_H__ion_Intermembrane_space
sa13_Cyt_C_mitochondrial_matrix -> sa20_H__ion_Intermembrane_space
sa19_H__ion_mitochondrial_matrix -> sa20_H__ion_Intermembrane_space
sa255_QH_2__simple_molecule_mitochondrial_matrix -> sa20_H__ion_Intermembrane_space
complex_3_complex -> sa20_H__ion_Intermembrane_space
sa24_O_2__simple_molecule_mitochondrial_matrix -> O__2__endsuper__simple_molecule
sa13_Cyt_C_mitochondrial_matrix -> O__2__endsuper__simple_molecule
sa19_H__ion_mitochondrial_matrix -> O__2__endsuper__simple_molecule
sa255_QH_2__simple_molecule_mitochondrial_matrix -> O__2__endsuper__simple_molecule
complex_3_complex -> O__2__endsuper__simple_molecule
ADP_simple_molecule -> ATP_simple_molecule
Pi_simple_molecule -> ATP_simple_molecule
ATP_Synthase_complex -> ATP_simple_molecule
sa335_H__ion_mitochondrial_matrix -> ATP_simple_molecule
csa84_complex_2_complex_mitochondrial_matrix -> sa220_QH_2__simple_molecule_mitochondrial_matrix
sa219_Q_simple_molecule_mitochondrial_matrix -> sa220_QH_2__simple_molecule_mitochondrial_matrix
Complex_1_complex -> sa220_QH_2__simple_molecule_mitochondrial_matrix
sa24_O_2__simple_molecule_mitochondrial_matrix -> sa253_Cyt_C_mitochondrial_matrix
sa13_Cyt_C_mitochondrial_matrix -> sa253_Cyt_C_mitochondrial_matrix
sa19_H__ion_mitochondrial_matrix -> sa253_Cyt_C_mitochondrial_matrix
sa255_QH_2__simple_molecule_mitochondrial_matrix -> sa253_Cyt_C_mitochondrial_matrix
complex_3_complex -> sa253_Cyt_C_mitochondrial_matrix
ATP_Synthase_complex -> sa335_H__ion_mitochondrial_matrix
H_2_O_2__simple_molecule -> sa354_superoxide_simple_molecule_mitochondrial_matrix
hydroxide_simple_molecule -> sa354_superoxide_simple_molecule_mitochondrial_matrix
sa374_O_2__simple_molecule_mitochondrial_matrix -> sa354_superoxide_simple_molecule_mitochondrial_matrix
sa354_superoxide_simple_molecule_mitochondrial_matrix -> H_2_O_2__simple_molecule
sa373_H__ion_mitochondrial_matrix -> H_2_O_2__simple_molecule
SOD1 -> H_2_O_2__simple_molecule
sa360_superoxide_simple_molecule_mitochondrial_matrix -> H_2_O_2__simple_molecule
sa371_H__ion_mitochondrial_matrix -> H_2_O_2__simple_molecule
SOD2 -> H_2_O_2__simple_molecule
H_2_O_2__simple_molecule -> sa356_H_2_O_simple_molecule_mitochondrial_matrix
sa392_TXN2_mitochondrial_matrix -> sa356_H_2_O_simple_molecule_mitochondrial_matrix
PRDX_complex -> sa356_H_2_O_simple_molecule_mitochondrial_matrix
glutathione_simple_molecule -> sa356_H_2_O_simple_molecule_mitochondrial_matrix
GPX4 -> sa356_H_2_O_simple_molecule_mitochondrial_matrix
GPX1 -> sa356_H_2_O_simple_molecule_mitochondrial_matrix
CAT -> sa356_H_2_O_simple_molecule_mitochondrial_matrix
sa359_SIRT3_mitochondrial_matrix -> SOD2
sa361_O_2__simple_molecule_mitochondrial_matrix -> sa360_superoxide_simple_molecule_mitochondrial_matrix
paraquat_simple_molecule -> sa360_superoxide_simple_molecule_mitochondrial_matrix
sa360_superoxide_simple_molecule_mitochondrial_matrix -> ROS_simple_molecule
sa354_superoxide_simple_molecule_mitochondrial_matrix -> ROS_simple_molecule
hydroxide_simple_molecule -> ROS_simple_molecule
H_2_O_2__simple_molecule -> ROS_simple_molecule
H_2_O_2__simple_molecule -> HO_simple_molecule
sa365_Fe2__ion_mitochondrial_matrix -> HO_simple_molecule
hydroxide_simple_molecule -> HO_simple_molecule
sa367_Fe2__ion_mitochondrial_matrix -> HO_simple_molecule
H_2_O_2__simple_molecule -> hydroxide_simple_molecule
sa365_Fe2__ion_mitochondrial_matrix -> hydroxide_simple_molecule
H_2_O_2__simple_molecule -> sa366_Fe3__ion_mitochondrial_matrix
sa365_Fe2__ion_mitochondrial_matrix -> sa366_Fe3__ion_mitochondrial_matrix
hydroxide_simple_molecule -> sa368_Fe3__ion_mitochondrial_matrix
sa367_Fe2__ion_mitochondrial_matrix -> sa368_Fe3__ion_mitochondrial_matrix
H_2_O_2__simple_molecule -> sa369_H_2_O_simple_molecule_mitochondrial_matrix
hydroxide_simple_molecule -> sa369_H_2_O_simple_molecule_mitochondrial_matrix
H_2_O_2__simple_molecule -> sa370_H__ion_mitochondrial_matrix
hydroxide_simple_molecule -> sa370_H__ion_mitochondrial_matrix
sa354_superoxide_simple_molecule_mitochondrial_matrix -> sa374_O_2__simple_molecule_mitochondrial_matrix
sa376_Fe3__ion_mitochondrial_matrix -> sa374_O_2__simple_molecule_mitochondrial_matrix
H_2_O_2__simple_molecule -> glutathione_disulfide_simple_molecule
glutathione_simple_molecule -> glutathione_disulfide_simple_molecule
GPX4 -> glutathione_disulfide_simple_molecule
GPX1 -> glutathione_disulfide_simple_molecule
glutathione_disulfide_simple_molecule -> glutathione_simple_molecule
sa382_NADPH_simple_molecule_mitochondrial_matrix -> glutathione_simple_molecule
GSR -> glutathione_simple_molecule
glutathione_disulfide_simple_molecule -> sa383_NADP____simple_molecule_mitochondrial_matrix
sa382_NADPH_simple_molecule_mitochondrial_matrix -> sa383_NADP____simple_molecule_mitochondrial_matrix
GSR -> sa383_NADP____simple_molecule_mitochondrial_matrix
H_2_O_2__simple_molecule -> sa391_TXN2_mitochondrial_matrix
sa392_TXN2_mitochondrial_matrix -> sa391_TXN2_mitochondrial_matrix
PRDX_complex -> sa391_TXN2_mitochondrial_matrix
sa391_TXN2_mitochondrial_matrix -> sa392_TXN2_mitochondrial_matrix
sa395_NADPH_simple_molecule_mitochondrial_matrix -> sa392_TXN2_mitochondrial_matrix
TXNRD2 -> sa392_TXN2_mitochondrial_matrix
sa391_TXN2_mitochondrial_matrix -> sa394_NADP____simple_molecule_mitochondrial_matrix
sa395_NADPH_simple_molecule_mitochondrial_matrix -> sa394_NADP____simple_molecule_mitochondrial_matrix
TXNRD2 -> sa394_NADP____simple_molecule_mitochondrial_matrix
paraquat_dication_complex -> paraquat_simple_molecule
sa360_superoxide_simple_molecule_mitochondrial_matrix -> paraquat_simple_molecule
Complex_1_complex -> paraquat_simple_molecule
mt_DNA_gene -> mt_mRNA_rna
TFAM -> mt_mRNA_rna
MT_transcription_complex -> mt_mRNA_rna
damaged_mt_DNA_gene -| mt_mRNA_rna
TFAM -> mt_DNA_replication_phenotype
Mt_replication_complex -> mt_DNA_replication_phenotype
Mt_dNTP_pool_complex -> mt_DNA_replication_phenotype
complex_3_complex -> sa644_H__ion_Intermembrane_space
NADH_simple_molecule -> sa649_H__ion_mitochondrial_matrix
Complex_1_complex -> sa649_H__ion_mitochondrial_matrix
mt_DNA_damage_phenotype -| mt_DNA_gene
mt_DNA_replication_phenotype -> mt_DNA_gene
damaged_mt_DNA_gene -> mt_DNA_gene
TFAM -> mt_DNA_gene
Mt_DNA_repair_complex -> mt_DNA_gene
Mt_dNTP_pool_complex -> mt_DNA_gene
mt_DNA_gene -> damaged_mt_DNA_gene
mt_DNA_damage_phenotype -> damaged_mt_DNA_gene
Orf9c -| NDUFB9
Orf9c -| NDUFA1
Orf9c -| ECSIT
Orf9c -| ACAD9
Nsp7 -| NDUFAF7
TOM_complex_complex -> precursor_protein_N_terminus_binding
TIM22_complex_complex -> precursor_protein_N_terminus_binding
ORF9b -| precursor_protein_N_terminus_binding
TIM23_complex_complex -> precursor_protein_N_terminus_binding
TIM9_TIM10_complex_complex -> precursor_protein_N_terminus_binding
sa354_superoxide_simple_molecule_mitochondrial_matrix -> sa377_H__ion_mitochondrial_matrix
sa376_Fe3__ion_mitochondrial_matrix -> sa377_H__ion_mitochondrial_matrix
sa354_superoxide_simple_molecule_mitochondrial_matrix -> sa375_Fe2__ion_mitochondrial_matrix
sa376_Fe3__ion_mitochondrial_matrix -> sa375_Fe2__ion_mitochondrial_matrix
$ACAD9: !Orf9c
$ATP_Synthase_complex: (((sa20_H__ion_Intermembrane_space | sa644_H__ion_Intermembrane_space) | sa18_H__ion_Intermembrane_space) | (ATP5MG & !Nsp6))
$ATP_simple_molecule: (((ATP_Synthase_complex | sa335_H__ion_mitochondrial_matrix) & ADP_simple_molecule) & Pi_simple_molecule)
$Complex_1_complex: ((((NDUFA1 & NDUFB9) & csa98_mtDNA_encoded_OXPHOS_units_complex_mitochondrial_matrix) & OXPHOS_factors_complex) | (NADH_simple_molecule & Complex_1_complex))
$ECSIT: !Orf9c
$HO_simple_molecule: ((H_2_O_2__simple_molecule & sa365_Fe2__ion_mitochondrial_matrix) | (hydroxide_simple_molecule & sa367_Fe2__ion_mitochondrial_matrix))
$H_2_O_2__simple_molecule: (((sa354_superoxide_simple_molecule_mitochondrial_matrix & sa373_H__ion_mitochondrial_matrix) & SOD1) | ((sa360_superoxide_simple_molecule_mitochondrial_matrix & sa371_H__ion_mitochondrial_matrix) & SOD2))
$MT_tRNAs_complex: ((Mt_tRNA_synthetase_complex | TRMT1) & mt_DNA_gene)
$NAD__simple_molecule: (NADH_simple_molecule & Complex_1_complex)
$NDUFA1: !Orf9c
$NDUFAF7: !Nsp7
$NDUFB9: !Orf9c
$Nsp8_affected_Mt_ribosomal_proteins_complex: !Nsp8
$OXPHOS_factors_complex: ((ACAD9 & ECSIT) & NDUFAF7)
$O__2__endsuper__simple_molecule: ((((sa24_O_2__simple_molecule_mitochondrial_matrix & sa13_Cyt_C_mitochondrial_matrix) & sa19_H__ion_mitochondrial_matrix) & sa255_QH_2__simple_molecule_mitochondrial_matrix) & complex_3_complex)
$ROS_simple_molecule: (((sa360_superoxide_simple_molecule_mitochondrial_matrix | sa354_superoxide_simple_molecule_mitochondrial_matrix) | hydroxide_simple_molecule) | H_2_O_2__simple_molecule)
$SOD2: sa359_SIRT3_mitochondrial_matrix
$TIM22_complex_complex: (TIMM29 & !NSP4)
$TIM9_TIM10_complex_complex: !NSP4
$complex_3_complex: ((csa103_mtDNA_encoded_OXPHOS_units_complex_mitochondrial_matrix & OXPHOS_factors_complex) | (Complex_1_complex & sa219_Q_simple_molecule_mitochondrial_matrix))
$complex_4_complex: ((csa103_mtDNA_encoded_OXPHOS_units_complex_mitochondrial_matrix & OXPHOS_factors_complex) | (complex_3_complex & sa253_Cyt_C_mitochondrial_matrix))
$csa24_complex_2_complex_mitochondrial_matrix: ((sa205_SIRT3_mitochondrial_matrix | OXPHOS_factors_complex) | ((csa84_complex_2_complex_mitochondrial_matrix & sa219_Q_simple_molecule_mitochondrial_matrix) & Complex_1_complex))
$csa60_mtDNA_encoded_OXPHOS_units_complex_mitochondrial_matrix: (((Mt_translation_complex | Mt_ribosomal_proteins_complex) | Nsp8_affected_Mt_ribosomal_proteins_complex) & mt_mRNA_rna)
$csa84_complex_2_complex_mitochondrial_matrix: (csa24_complex_2_complex_mitochondrial_matrix & TCA_phenotype)
$damaged_mt_DNA_gene: (mt_DNA_gene & mt_DNA_damage_phenotype)
$glutathione_disulfide_simple_molecule: (((GPX4 | GPX1) & H_2_O_2__simple_molecule) & glutathione_simple_molecule)
$glutathione_simple_molecule: ((glutathione_disulfide_simple_molecule & sa382_NADPH_simple_molecule_mitochondrial_matrix) & GSR)
$hydroxide_simple_molecule: (H_2_O_2__simple_molecule & sa365_Fe2__ion_mitochondrial_matrix)
$mt_DNA_gene: ((mt_DNA_replication_phenotype & !mt_DNA_damage_phenotype) | (((TFAM | Mt_DNA_repair_complex) | Mt_dNTP_pool_complex) & damaged_mt_DNA_gene))
$mt_DNA_replication_phenotype: ((TFAM | Mt_replication_complex) | Mt_dNTP_pool_complex)
$mt_mRNA_rna: (((TFAM | MT_transcription_complex) & mt_DNA_gene) & !damaged_mt_DNA_gene)
$paraquat_dication_complex: (paraquat_simple_molecule & sa361_O_2__simple_molecule_mitochondrial_matrix)
$paraquat_simple_molecule: ((sa360_superoxide_simple_molecule_mitochondrial_matrix | Complex_1_complex) & paraquat_dication_complex)
$precursor_protein_N_terminus_binding: ((((TOM_complex_complex | TIM22_complex_complex) | TIM23_complex_complex) | TIM9_TIM10_complex_complex) & !ORF9b)
$sa18_H__ion_Intermembrane_space: Complex_1_complex
$sa20_H__ion_Intermembrane_space: ((((sa24_O_2__simple_molecule_mitochondrial_matrix & sa13_Cyt_C_mitochondrial_matrix) & sa19_H__ion_mitochondrial_matrix) & sa255_QH_2__simple_molecule_mitochondrial_matrix) & complex_3_complex)
$sa220_QH_2__simple_molecule_mitochondrial_matrix: ((csa84_complex_2_complex_mitochondrial_matrix & sa219_Q_simple_molecule_mitochondrial_matrix) & Complex_1_complex)
$sa253_Cyt_C_mitochondrial_matrix: ((((sa24_O_2__simple_molecule_mitochondrial_matrix & sa13_Cyt_C_mitochondrial_matrix) & sa19_H__ion_mitochondrial_matrix) & sa255_QH_2__simple_molecule_mitochondrial_matrix) & complex_3_complex)
$sa335_H__ion_mitochondrial_matrix: ATP_Synthase_complex
$sa354_superoxide_simple_molecule_mitochondrial_matrix: ((H_2_O_2__simple_molecule & hydroxide_simple_molecule) | sa374_O_2__simple_molecule_mitochondrial_matrix)
$sa356_H_2_O_simple_molecule_mitochondrial_matrix: ((((H_2_O_2__simple_molecule & sa392_TXN2_mitochondrial_matrix) & PRDX_complex) | (((GPX4 | GPX1) & H_2_O_2__simple_molecule) & glutathione_simple_molecule)) | (H_2_O_2__simple_molecule & CAT))
$sa360_superoxide_simple_molecule_mitochondrial_matrix: (sa361_O_2__simple_molecule_mitochondrial_matrix | (paraquat_simple_molecule & sa361_O_2__simple_molecule_mitochondrial_matrix))
$sa366_Fe3__ion_mitochondrial_matrix: (H_2_O_2__simple_molecule & sa365_Fe2__ion_mitochondrial_matrix)
$sa368_Fe3__ion_mitochondrial_matrix: (hydroxide_simple_molecule & sa367_Fe2__ion_mitochondrial_matrix)
$sa369_H_2_O_simple_molecule_mitochondrial_matrix: (H_2_O_2__simple_molecule & hydroxide_simple_molecule)
$sa370_H__ion_mitochondrial_matrix: (H_2_O_2__simple_molecule & hydroxide_simple_molecule)
$sa374_O_2__simple_molecule_mitochondrial_matrix: (sa354_superoxide_simple_molecule_mitochondrial_matrix & sa376_Fe3__ion_mitochondrial_matrix)
$sa375_Fe2__ion_mitochondrial_matrix: (sa354_superoxide_simple_molecule_mitochondrial_matrix & sa376_Fe3__ion_mitochondrial_matrix)
$sa377_H__ion_mitochondrial_matrix: (sa354_superoxide_simple_molecule_mitochondrial_matrix & sa376_Fe3__ion_mitochondrial_matrix)
$sa383_NADP____simple_molecule_mitochondrial_matrix: ((glutathione_disulfide_simple_molecule & sa382_NADPH_simple_molecule_mitochondrial_matrix) & GSR)
$sa391_TXN2_mitochondrial_matrix: ((H_2_O_2__simple_molecule & sa392_TXN2_mitochondrial_matrix) & PRDX_complex)
$sa392_TXN2_mitochondrial_matrix: ((sa391_TXN2_mitochondrial_matrix & sa395_NADPH_simple_molecule_mitochondrial_matrix) & TXNRD2)
$sa394_NADP____simple_molecule_mitochondrial_matrix: ((sa391_TXN2_mitochondrial_matrix & sa395_NADPH_simple_molecule_mitochondrial_matrix) & TXNRD2)
$sa644_H__ion_Intermembrane_space: complex_3_complex
$sa649_H__ion_mitochondrial_matrix: (NADH_simple_molecule & Complex_1_complex)
$sa6_Q_simple_molecule_mitochondrial_matrix: ((((sa24_O_2__simple_molecule_mitochondrial_matrix & sa13_Cyt_C_mitochondrial_matrix) & sa19_H__ion_mitochondrial_matrix) & sa255_QH_2__simple_molecule_mitochondrial_matrix) & complex_3_complex)